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Cheap flights from GUA to Panama City

Recently found return fares from $305, with October the cheapest month we know of. Compare dates, then book with the partner you choose.

Cheapest months to fly

Lowest recently found return fare in each month. Tap a month to see that month's calendar.

$305 Oct2026 $305 Nov2026 $314 Dec2026 $341 Jan2027

GUA → Panama City

November 2026

Mon Tue Wed Thu Fri Sat Sun 1 2 3 $305 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 $340 27 28 29 30
LowerHigherLowest this month

Lowest fares for the best day

  • AviancaFri 13 Nov – Fri 20 Nov · 1 stop · 2h 55m $369
See all flights for these dates

Airport in Panama City

  • PTYTocumen

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GUA
PTY

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More trips from GUA

All flights from GUA Panama City to GUA flights
FRSfrom $186 Mexico Cityfrom $269 Cancunfrom $279 Atlantafrom $369 CTGfrom $381 MGAfrom $391 SALfrom $420 Limafrom $459

FAQ

Questions about this route

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Help center Contact us
01What is the cheapest month to fly from GUA to Panama City?

Based on recently found fares, October 2026 has the lowest price we know of, from $305. Prices change often, so check the calendar for current fares.

02Are the prices on this page final?

No. They are recently found fares. When you open a deal, the partner shows the live price, including taxes and fees, before you pay.

03How can I get an alert when flights to Panama City get cheaper?

Use the price alert on this page. Choose your dates or a whole month and we will email you when the fare drops.